| To Register SMDM Homepage | |
|
|
|
||||
Purpose: In order provide guidance on which of six different health utility measures to use when assessing the desirability of a health state, research that used these measures within HIV populations was reviewed.
Methods: Ovid and PubMed were used to find all peer reviewed research articles (from 1966 to Jan 2004) in which people with HIV were asked to assess the desirability of their own health state using at least one of six health utility measures: Rating Scale (RS), Standard Gamble (SG), Time Tradeoff (TTO), Health Utility Index (HUI), EuroQol (EQ-5D), or Quality of Well-Being Scale (QWB). Information concerning the reliability, validity, and responsiveness for these six health utility measures was extracted.
Results: The review yielded 36 articles. No articles were found in which the retest reliability or the internal consistency of these measures were specifically tested. The difference in health utility between people classified as having HIV versus AIDS depends on the measure (see table). The RS and EQ-5D seem to be responsive to changes in health. There is a decent amount of information available on the construct validity of the RS, EQ-5D, and QWB, but there is little information on the SG, TTO, and HUI. The RS, EQ-5D, and QWB all correlate reasonably well with health status measures and markers of disease progression, while the SG and TTO do not.
Conclusions: Evidence for the reliability of these measures within HIV populations is desperately needed. Whether the measures differ in validity ultimately rests on both empirical evidence, as presented in this review, and rational argument for whether they are tapping into the construct of interest. Based on the available empirical evidence within HIV populations, the RS, EQ-5D, and QWB seem to have the most desirable measurement qualities.
See more of Poster Session - Utility Theory; Health Economics; Patient & Physician Preferences; Simulation; Technology Assessment
See more of The 26th Annual Meeting of the Society for Medical Decision Making (October 17-20, 2004)