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Methods: We enrolled participants between the ages of 30 and 75 without previous coronary disease. Each participant was asked to respond to hypothetical patient scenario about heart disease (e.g. a 50 year-old man with a moderate risk (13%) of a heart attack occurring in the next 10 years) using their own values. Participants completed a values elicitation exercise using conjoint analysis; responses were used to calculate part-worth utilities. We then used a pre-defined attribute algorithm for treatment options along with each participant's part-worth utilities to identify his or her optimal treatment choice to prevent a heart attack. Treatment choices included aspirin, blood pressure medication, cholesterol medication, or physical activity 30-40 minutes 3 times per week. The generated choice was compared with the treatment choice each participant selected after the values elicitation exercise. Participants selected their preferred treatment choice without knowing the treatment choice generated by their responses to the values elicitation exercise.
Results: 113 participants completed the study. Average age was 51 years old, 29% were male, and 52% white and 42% were African American. Most (52%) had completed a 4-year college degree of more. After the values elicitation exercise using conjoint analysis most (65%) selected physical activity as their preferred choice. 54% of participants had different selected and conjoint-generated treatment choices.
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|
Conjoint-Generated Treatment Choice |
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|
Aspirin |
Blood Pressure Medication |
Cholesterol Medication |
Physical Activity |
|
Participant Selected Treatment Choice |
Aspirin |
6% |
11% |
0% |
3% |
Blood Pressure Medication |
4% |
5% |
0% |
4% |
|
Cholesterol Medication |
0% |
1% |
0% |
2% |
|
Physical Activity |
8% |
22% |
0% |
35% |
Conclusion: Conjoint analysis produced different treatment choices than those directly elicited from participants. These differences may have implications for the use of conjoint analysis to elicit values and identify optimal treatment choices. This technique may be an mportant tool to help providers and patients communicate and reach treatment choice decisions.