TRA-3 COLOSTOMY IS BETTER THAN DEATH, BUT A 4% CHANCE OF DEATH MIGHT BE BETTER THAN A 4% CHANCE OF COLOSTOMY: WHY PEOPLE MAKE CHOICES SEEMINGLY AT ODDS WITH THEIR STATED PREFERENCES

Monday, October 25, 2010: 9:15 AM
Grand Ballroom East (Sheraton Centre Toronto Hotel)
Holly Witteman, PhD1, Peter A. Ubel, MD2, Andrea M. Angott, M.S.1, Andrea Fuhrel-Forbis, M.A.1, Angela Fagerlin, PhD3 and Brian J. Zikmund-Fisher, PhD1, (1)University of Michigan, Ann Arbor, MI, (2)University of Michigan, Ann Arbor, USA, (3)Internal Medicine, Ann Arbor, MI

Purpose: When asked for their preference between death and colostomy, most people say that they prefer colostomy. However, when given the choice of two hypothetical treatments that differ only in that one has four percent chance of colostomy while the other has four percent additional chance of death, approximately 25% of people who say that they prefer colostomy actually opt for the additional chance of death. This study examined whether probability-sensitive preference weighting may help to explain why people make these types of treatment choices that are inconsistent with their stated preferences.

Method: 1656 participants in a demographically diverse online survey were randomly assigned to indicate their preference by answering either, “If you had to choose, would you rather die, or would you rather have a colostomy?” or, “If you had to choose, would you rather have a 4% chance of dying, or would you rather have a 4% chance of having a colostomy?” They were then asked to imagine that they had been diagnosed with colon cancer and were faced with a choice between two treatments, one with an uncomplicated cure rate of 80% and a 20% death rate, and another with an uncomplicated cure rate of 80%, a 16% death rate, and a 4% rate of colostomy.

Result: Consistent with our prior research, most people whose preferences were elicited with the first question stated that they preferred colostomy (80% of participants) to death (20%), but many then made a choice inconsistent with that preference (59% chose the treatment with higher chance of colostomy; 41% chose the treatment with higher chance of death). Compared to the first group, participants whose preferences were elicited with the 4% question preferred death (31%) over colostomy (69%) more often (Chi-squared = 24.31, p<.001) and their treatment choices were more concordant with their stated preferences (64% chose the treatment with higher chance of colostomy; 36% chose the treatment with higher chance of death, Chi-squared for concordance = 36.92, p<.001).

Conclusion: Our experiment suggests that probability-sensitive preference weighting may help explain why people’s medical treatment choices are sometimes at odds with their stated preferences. These findings also suggest that preference elicitation methods may not necessarily assume independence of probability levels and preference weights.