Purpose: To compare end-of-life health care costs in patients with non-small cell lung cancer (NSCLC) in Ontario, Canada, and the United States (US) Medicare program using cancer registry and administrative data.
Method: Two multidisciplinary teams collaborated to define comparable cohorts, health care services, and analyses. Patients with NSCLC who died from cancer in 2001-2005 were selected from the Ontario Cancer Registry and the US SEER cancer registry linked to Medicare claims. Inclusion criteria: survival >30 days post-diagnosis; age >65.5 at death; no lung cancer surgery within 1 year post-diagnosis (proxy for advanced stage, not recorded in Ontario data). Ontario administrative databases track service delivery. US Medicare claims are recorded in files submitted by hospitals, physicians, and other providers. Services categorized differently by Medicare than in Ontario data were re-defined for comparability. Eg., Ontario combined costs for adjoining ER visits and hospitalizations, and costed stand-alone ER visits separately. Chemotherapy drug, physician, equipment, and overhead costs are claimed separately in Medicare. Ontario distinguished physician, some expensive drugs, and all other costs. Resources that could not be costed comparatively were excluded; eg. outpatient prescription drugs, medical equipment. Examples of methods are below.
Service | SEER-Medicare files | Ontario | |
Data | costing | ||
hospitalizations | MEDPAR | CIHI Discharge Abstract Database | resource intensity weight * cost per weighted case |
emergency room (ER) | Outpatient | National Ambulatory Care Reporting System (NACRS) | |
chemotherapy | Carrier, Outpatient | NACRS | |
expensive chemotherapy drugs | Carrier, Outpatient | New Drug Funding Program | drug costs in data |
Physician services | Carrier | Claims History Database of the Ontario Health Insurance Plan | fee-for-service claims |
Result: In the month before death, mean total costs in Ontario were $11,538 and Medicare payments were $9,556. Higher US chemotherapy payments were balanced by higher Ontario inpatient costs. Estimates exclude patient out-of-pocket costs or payments from other insurers, approximately 40% of US and 5% of Ontario total direct medical costs for these resources.
Conclusion: Cross-country comparisons require significant effort, and knowledge of reimbursement policies and databases, to define similar patients, services, and costs. Some cannot be compared. Despite challenges, such collaborations are underway and offer rich opportunities to improve estimation of international cancer costs.
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