Method: This retrospective cohort study was undertaken on 70 patients based on insured database for six-month period (October 2010 through March 2011) in Haji Adam Malik (HAM) Hospital, Indonesia. Inclusion criteria were patients diagnosed with pneumonia and 18years old or above. Data collected include type of drugs administered, supporting laboratory tests, and clinical outcomes. Characteristics of the patients were analyzed using descriptive statistics in SPSS program version 19. Occurrence of DRPs (but limited only to indication without drugs, wrong provided antibiotic dose, and drug interactions) was analyzed using Stockley’s drug interaction, Medline, and Clinical Drug Data. Association among DRPs and LOS was analyzed applying multiple linear regression in the SPSS program version 19.
Result: Characteristics of the sample population: male, 51.40%, female was 48.60%. Mean age of the patients was (51.63 with standard deviation of 15.56) years. Means of incidence of: indication without drugs, 0.01±0.12; wrong antibiotic dose, 0.10±0.30; drug interaction, 0.81±0.87. Mean LOS was (10.50 with standard deviation of 7.07) days. Multiple linear equation obtained: LOS = 8.40 + 2.60 indication without drug + 4.13 antibiotics wrong dose + 2.03 drug interaction. Linear regression analysis indicated a weak association among DRPs and LOS (R2=0.12). This study showed that antibiotics wrong dose had the highest impact on hospital LOS of the pneumonia patients.
Conclusion: Occurrence of DRPs in the management of pneumonia in HAM Hospital was high. In the future, these DRPs must be highlighted to improve the patients’ outcomes.